Carbaryl curbed

Carbaryl, a carbamate insecticide in use for over 40 years as a treatment for head lice on children, in horticulture, public health and the home as well as a worm killer on turf, has been declared a potential human carcinogen by the UK Government Committee on Carcinogenicity. Restrictions have been imposed on its use, and some approvals revoked.

A joint announcement detailing restrictions to carbaryl use in the UK was made by the Ministry of Agriculture Fisheries and Food (MAFF) Pesticide Safety Directorate and the Health and Safety Executive (HSE) on 7 November. Carbaryl will no longer be approved for non-professional uses; will be available for medical uses only by prescription; and professional use is subject to restrictions designed to limit operator exposure.
    The decision follows an assessment by the government's Committee on Carcin-ogenicity (COC), based on manufacturer's test data (not made available to the public), which concluded that carbaryl should be considered a potential human carcinogen.
    Carbaryl's use as an insecticide in the treatment of head lice was the most widely reported aspect following the announcement. It is one of several such insecticides including lindane, permethrin and d-phenothrin. The problems of domestic use of pyrethroids have been raised in Germany, with regulators concerned about carcinogenicity (PN29, p. 3).
    As a result of the COC findings the Department of Health restricted carbaryl-based head lice treatments to prescriptions only. The Chief Medical Officer advised health professionals to recommend treatments based on malathion, permethrin and other synthetic pyrethroids. He also referred to the Bug Busting programme promoted by Community Hygiene Concern (see PN29, p. 17). Carbaryl's new prescription only status may not reduce its use, but may increase the burden on doctors-and the overall health bill.
    Carbaryl has played a role in lice treatment rotation programmes aimed at avoiding louse resistance. The new restrictions may disrupt this programme, or result in increased use of other treatments such as those containing lindane.
    In the public health sector carbaryl's main recent uses have been in wasp nest destruction and ant control. MAFF and HSE advise using alternative products based on synthetic pyrethroids, organophosphates or other carbamate insecticides. Recommended replacements for carbaryl in the control of mites, lice and insects in poultry houses include alpha-cypermethrin (WHO class II toxicity, highly toxic to bees), dichlorvos (WHO class Ib toxicity, cholinesterase inhibitor, eye and skin irritant, classed as a possible human carcinogen by IARC and EPA and on the UK Red List) and fenitrothion (WHO class II toxicity, cholinesterase inhibitor and on the UK Red List).
    In its role as a lumbricide (worm killer) on turf, carbaryl will continue to be approved for use by professionals, subject to the conditions. According to the Sports Turf Research Institute (STRI) carbaryl is the least effective lumbricide currently in use. Carbendazim (a fungicide) and a mixture of lindane (organochlorine insecticide classified as a probable human carcinogen by the US EPA and a possible human carcinogen by IARC, on the UK Red List, an endocrine disruptor and toxic to wildlife) with thiophanate methyl (a fungicide classed as a possible human carcinogen by the US EPA) are more effective and far more widely used. STRI has done some research into alternative worm control strategies, but work has been interrupted because of breaks in funding.
    In UK agriculture, carbaryl is used on apples as a thinning agent and insecticide. In 1992 it was the seventh most extensively used pesticide by weight, on top fruit with 20.56 tons being applied over an area of 15,087 ha(1). This use will be subject to new conditions which will be stated on product labels.

Carbaryl-new restrictions

 Carbaryl is also used in veterinary medicine on products such as pet flea collars. The Veterinary Products Committee is considering restricting these uses.
    The UK authorities reacted swiftly and decisively to restrict the use of carbaryl in the wake of the report from the COC. A number of questions arise from this decision, such as:

1. Pesticide Usage Survey Group, Pesticide Usage Survey Report 115: Orchards and Fruit Stores in Great Britain 1992, MAFF 1994. See also Pesticide Usage Survey Group, Pesticide Usage Survey Report 120: Hardy Nursery Stock in Great Britain 1993, MAFF 1995.

[This article first appeared in Pesticides News No. 30, December 1995, page 5]